PNA forms an i-motif |
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Authors: | Krishnan-Ghosh Yamuna Stephens Elaine Balasubramanian Shankar |
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Institution: | National Centre for Biological Sciences, TIFR, UAS-GKVK Campus, Bellary Road, Bangalore 560 065, India. yamuna@ncbs.res.in |
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Abstract: | A C-rich PNA hexanucleotide, p(C5T), has been shown to form an i-motif by nanoelectrospray ionization mass spectrometry coupled with H/D exchange, to have thermal stability comparable with its DNA analogue, but to exist over a much narrower pH range. |
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