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A simple and efficient synthesis of (±)-mesembrine |
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| Authors: | Subhash P. Chavan Dushant A. Khobragade Ashok B. Pathak U.R. Kalkote |
| Affiliation: | Division of Organic Chemistry: Technology, National Chemical Laboratory, Pune 411008, India |
| Abstract: | A simple and efficient synthesis of (±)-mesembrine 1 is described employing double Michael addition and as the key step in 18% overall yield. |
| Keywords: | Alkaloids Michael addition Wittig reaction Protection Deprotection |
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