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Convenient synthesis of furan-3-carboxylic acid and derivatives
Authors:Nilo Zanatta  Débora Faoro  Simone C Silva  Helio G Bonacorso  Marcos AP Martins
Institution:Núcleo de Química de Heterociclos (NUQUIMHE), Departamento de Química, Universidade Federal de Santa Maria, 97.105-900 Santa Maria, RS, Brazil
Abstract:A convenient synthesis of furan-3-carboxylic acid and derivatives from aromatization of 4-trichloroacetyl-2,3-dihydrofuran followed by nucleophilic displacement of the trichloromethyl group by hydroxide, alcohols, and amines, is presented.
Keywords:Furan  Furan-3-acyl  Dihydrofuran
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