Simple deprotection of acetal type protecting groups under neutral conditions |
| |
| Authors: | Hideyoshi Miyake Takatsugu Tsumura Mitsuru Sasaki |
| |
| Affiliation: | Department of Agriculture, Kobe University, Rokkodai, Nada-ku, Kobe 657-8501, Japan |
| |
| Abstract: | When acetals such as MOM ethers, MEM ethers, and THP ethers were heated in ethylene glycol or propylene glycol, solvolysis proceeded smoothly to produce alcohols in excellent yield. This reaction is a very promising method for chemoselective deprotection of acetal type protecting groups. |
| |
| Keywords: | Deprotection Acetal Ethylene glycol Propylene glycol |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
