|
|||||
|
|
An innovative approach to the synthesis of annelated [a]diaza-anthracenones through tandem cyclization |
|
| Authors: | Ashoke Sharon Raja Roy |
| Institution: | a Molecular and Structural Biology Division, Central Drug Research Institute, Lucknow 226001, India b Sophisticated Analytical Instrument Facility, Central Drug Research Institute, Lucknow 226001, India c Medicinal Chemistry Division, Central Drug Research Institute, Lucknow 226001, India |
| Abstract: | An innovative route for the synthesis of a novel class of 4-aryl-11-oxo-1,2,3,11-tetrahydro-1,3a-diazacyclopentaa]anthracene-6-carbonitriles 5a-h and 5-aryl-12-oxo-1,3,4,12-tetrahydro-2H-1,4a-diazabenzoa]anthracene-7-carbonitriles 5i-k has been developed by ring transformation of suitably functionalized 2H-pyran-2-ones 1 with α-oxoketene cyclic aminals 2 to give compounds 4 followed by photo-induced cyclization. |
| Keywords: | Photocyclization X-ray diffraction Ring transformation reactions Reaction mechanism |
| 本文献已被 ScienceDirect 等数据库收录！ | |