Vitamin D side chain triazole analogs via cycloaddition `click' chemistry |
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Authors: | Byung-Chul Suh Steven M Silverman |
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Institution: | Department of Chemistry, School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD 21218, USA |
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Abstract: | Cycloaddition of a vitamin D side chain terminal acetylene with phenyl azide and separately with a vitamin D side chain terminal azide produced the corresponding 1,2,3-triazole monomeric and dimeric analogs of 1α-hydroxyvitamin D3 in good yields. |
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Keywords: | Vitamin D Triazole `Click' chemistry |
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