A simple reduction of methyl aromatic esters to alcohols using sodium borohydride-methanol system |
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Authors: | Núbia Boechat |
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Institution: | FioCruz-Fundação Oswaldo Cruz, Instituto de Tecnologia em Fármacos-Far Manguinhos. Rua Sizenando Nabuco, 100, Manguinhos, 21041-250 Rio de Janeiro-RJ, Brazil |
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Abstract: | Several aromatic esters were reduced to the corresponding alcohol by using sodium borohydride-methanol system. The reduction was completed within 2.0-4.0 h after refluxing in THF. The alcohol products were isolated after aqueous workup in good yields (88-97%). |
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Keywords: | NaBH4 Aromatic esters |
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