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Total synthesis of d-(+)-biotin
Authors:Subhash P. Chavan  Guduru Ramakrishna  Mohan M. Bhadbhade
Affiliation:a Division of Organic Chemistry: Technology, National Chemical Laboratory, Pashan, Pune 411008, India
b Center for Materials Characterization, National Chemical Laboratory, Pashan, Pune 411008, India
Abstract:
A total synthesis of d-(+)-biotin is described starting from d-(+)-glucosamine using acyliminium chemistry.
Keywords:d-(+)-Biotin   Glucosamine   Hydroxy imidazolidinones   Acyliminium ion   Wittig olefination
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