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Total synthesis of the marine cytotoxic caulibugulones A-D |
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| Authors: | David Alagille Gilles D Tamagnan |
| Institution: | a Department of Psychiatry, Yale University and VAHCS, 950 Campbell Avenue, West Haven, CT 06516, USA b Institute for Neurodegenerative Disorders, 60 Temple Street, Suite 8B, New Haven, CT 06510, USA |
| Abstract: | We report the first total synthesis of the cytotoxic marine alkaloids caulibugulone A-D. This synthesis confirmed the assigned structures and provided sufficient material for further biological testing. |
| Keywords: | Caulibugulones A-D Isoquinoline-5 8-diones Cytotoxicity |
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