Enantioselective total synthesis of epoxyquinone natural products (−)-phyllostine, (+)-epoxydon, (+)-epiepoxydon and (−)-panepophenanthrin: access to versatile chiral building blocks through enzymatic kinetic resolution |
| |
Authors: | Goverdhan Mehta Kabirul Islam |
| |
Affiliation: | Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India |
| |
Abstract: | A new enzyme mediated protocol to access versatile chiral building blocks for the synthesis of epoxyquinone natural products is delineated. Total syntheses of (−)-phyllostine, (+)-epoxydon, (+)-epiepoxydon and (−)-panepophenanthrin have been accomplished to demonstrate the efficacy of this approach. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|