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A convenient microwave assisted arylzinc generation-Negishi coupling protocol
Authors:Ilga Mutule
Affiliation:Latvian Institute of Organic Synthesis, Riga LV 1006, Latvia
Abstract:Arylzinc reagents were readily prepared from aryl iodides using a Zn-Cu couple in a microwave environment. A sequential arylzinc formation-Negishi cross-coupling protocol suitable for parallel high-throughput synthesis has been developed.
Keywords:Microwaves   Organometallic reagents   Zinc   Cross-coupling   Palladium   Nickel
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