A convenient microwave assisted arylzinc generation-Negishi coupling protocol |
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Authors: | Ilga Mutule |
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Affiliation: | Latvian Institute of Organic Synthesis, Riga LV 1006, Latvia |
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Abstract: | Arylzinc reagents were readily prepared from aryl iodides using a Zn-Cu couple in a microwave environment. A sequential arylzinc formation-Negishi cross-coupling protocol suitable for parallel high-throughput synthesis has been developed. |
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Keywords: | Microwaves Organometallic reagents Zinc Cross-coupling Palladium Nickel |
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