Synthesis of tetrazolopiperazine building blocks by a novel multi-component reaction |
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| Authors: | Michael Umkehrer,Jü rgen Kolb,Gü nther Ross |
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| Affiliation: | a Priaton GmbH, Discovery, Bahnhofstr. 9-15, D-82327 Tutzing, Germany
b Technical University Munich, Lichtenbergstr. 4, D-85747 Garching, Germany |
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| Abstract: | A novel Ugi-five-centre-four-component reaction (U-5C-4CR) of aldehydes, primary amines, trimethylsilylazide and 2-isocyanoethyltosylate yielding tetrazolopiperazine building blocks is described. |
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| Keywords: | Ugi-reaction Tetrazolopiperazines Combinatorial chemistry Isocyanoethyltosylate |
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