Diastereoselective allylzincation of γ-oxygenated vinyllithiums bearing functionalized side-chains

Allylzincation of γ-oxygenated vinyllithiums bearing functionalized side-chains proved to be more difficult than that reported in the case of γ-oxygenated vinyllithiums with unfunctionalized side-chains. However, when allylzincation occurs it gives the corresponding linear compounds with high diastereoselection as a consequence of the zinc being coordinated by the two oxygen atoms of the methoxymethyl ether moiety.