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An efficient and selective tosylation of alcohols with p-toluenesulfonic acid
Authors:Biswanath Das  V. Saidi Reddy  M. Ravinder Reddy
Affiliation:Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Abstract:Silica chloride has been found to be an efficient catalyst for facile tosylation of alcohols directly with p-toluenesulfonic acid in methylene chloride under reflux. The process is associated with selective tosylation of secondary alcohols over primary alcohols.
Keywords:Alcohols   p-TsOH   Tosylation   Silica chloride   Selectivity
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