cis-Carbocuperation of acetylenic sulfoxides and corresponding applications in the regio- and stereoselective synthesis of polysubstituted vinyl sulfoxides |
| |
| Authors: | Qing Xu |
| |
| Affiliation: | a Department of Chemistry, Zhejiang University (Xixi Campus), Hangzhou 310028, PR China
b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, PR China |
| |
| Abstract: | cis-Carbocuperation reaction of monoorganocopper reagent with acetylenic sulfoxides, followed by electrophilic reaction with a variety of electrophiles, provided a regio- and stereoselective method to prepare the versatile polysubstituted vinyl sulfoxides. Sonogashira cross-coupling reaction of the obtained α-iodovinyl sulfoxides with terminal acetylenes was also investigated to afford the versatile conjugate sulfinyl enynes. |
| |
| Keywords: | Carbocuperation Acetylenic sulfoxides Polysubstituted vinyl sulfoxides |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
