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Synthesis of 1-(2′-O-methyl-β-d-ribofuranosyl)-5-nitroindole and its phosphoramidite derivative |
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| Authors: | Gilles Gaubert |
| Affiliation: | Nucleic Acid Center, Department of Chemistry, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark |
| Abstract: | The synthesis of 1-(2′-O-methyl-β-d-ribofuranosyl)-5-nitroindole, a new nucleoside containing the universal base 5-nitroindole, and its phosphoramidite derivative for incorporation into oligonucleotides is described. |
| Keywords: | 5-Nitroindole ribonucleoside Phosphoramidite synthesis Universal hybridization Universal base 2&prime -O-Me-RNA Monomer |
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