A novel bromophenol from marine red alga <Emphasis Type="Italic">Symphyocladia latiuscula</Emphasis> |
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| Authors: | Xiuli Xu Fuhang Song Xiao Fan Nianqiao Fang Jiangong Shi |
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| Institution: | (1) School of Marine Science, China University of Geosciences, Beijing, 100083, P. R. China;(2) Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, P. R. China;(3) Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, P. R. China;(4) Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, P. R. China; |
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| Abstract: | 2,3,6-Tribromo-4,5-dihydroxybenzyl ethyl ether (1), a new bromophenol, was isolated from the ethanol extract of marine red alga Symphyocladia latiuscula, with a known compound, 2,3,6-tribromo-4,5-dihydroxybenzyl methyl ether (2). Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1 and 2-dimensional
NMR techniques. Compounds 1 and 2 showed inhibitory activity against Staphyloccocus aureus with IC50 102 and 50 μg/mL, respectively. |
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