Paraquat induces oxidative stress, neuronal loss in substantia nigra region and Parkinsonism in adult rats: Neuroprotection and amelioration of symptoms by water-soluble formulation of Coenzyme Q10 |
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| Authors: | Mallika Somayajulu-Ni?u Jagdeep K Sandhu Jerome Cohen Marianna Sikorska TS Sridhar Anca Matei Henryk Borowy-Borowski and Siyaram Pandey |
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| Institution: | (1) Chemistry & Biochemistry, University of Windsor, Windsor, ON, Canada;(2) Psychology, University of Windsor, Windsor, ON, Canada;(3) Institute for Biological Sciences, National Research Council Canada, Ottawa, ON, Canada;(4) St John's Research Institute, Bangalore, India |
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| Abstract: | Background Parkinson's disease, for which currently there is no cure, develops as a result of progressive loss of dopamine neurons in
the brain; thus, identification of any potential therapeutic intervention for disease management is of a great importance. |
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