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An Iminocoumarin Sulfonamide Based Turn‐On Fluorescent Probe for the Detection of Biothiols in Aqueous Solution |
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| Authors: | Yan‐Ling Yang Fu‐Ming Zhang Prof. Dr. Ya‐Wen Wang Bao‐Xin Zhang Prof. Dr. Ran Fang Prof. Dr. Jian‐Guo Fang Prof. Dr. Yu Peng |
| Affiliation: | 1. Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000 (P. R. China), Fax: (+86)?931‐8912582;2. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (P. R. China) |
| Abstract: | A new chemodosimeter for the highly selective sensing and imaging of biothiols was designed and realized in phosphate‐buffered saline solution at pH 7.4 through a fluorescence “off–on” response. A unique mechanism featuring a two‐step cascade (biothiols→H2O) sequence for this remarkable recognition is disclosed for the first time. |
| Keywords: | biothiols domino reactions chemodosimeter fluorescence molecular recognition |