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The natural diterpenoid kamebanin
Authors:Cui Rong Sun  Hao Shi  Yuan Jiang Pan
Abstract:Kamebanin, alternatively called rel‐(?)‐(1R,4R,8S,9R,10S,13S,16R)‐2,8,16‐tri­hydroxy‐5,5,9‐tri­methyl‐14‐methyl­enetetra­cyclo­11.2.1.01,10.04,9]­hexadecan‐15‐one, C20H30O4, is a natural diterpenoid which has cytotoxic and antibacterial activity. The mol­ecule is composed of three six‐membered rings, which all adopt chair conformations, and one five‐membered ring, which adopts an envelope conformation. The conjugated α‐­methyl­ene­cyclo­pentanone ring is the active part in the mol­ecule due to the ring strain. All three hydroxy groups serve as hydrogen‐bond donors and acceptors, forming a continuous two‐dimensional network.
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