one-pot synthesis of pyrrolo-[3,4-d]isoxazoline-4,6-diones via nitrile oxides |
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Authors: | J. Rajput B. Singh K. K. Singal |
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Affiliation: | (1) Department of Chemistry, Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, 144011, Punjab, India;(2) Department of Chemistry, Punjabi University, Patiala, 147 002, Punjab, India |
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Abstract: | 1,3-Dipolar cycloaddition of nitrile oxides generated in situ in the presence of variously substituted N-arylmaleimides and N-benzylmaleimide provides new pyrrolo[3,4-d]izoxazoline-4,6-diones in good yields. The whole procedure could be performed in a practical and efficient one-pot operation. All the cycloadducts were isolated in excellent yields and identified by spectral studies. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 444–448, March, 2009. |
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Keywords: | maleimides nitrile oxides regiospecific 1 3-dipolar cycloaddition |
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