one-pot synthesis of pyrrolo-[3,4-d]isoxazoline-4,6-diones via nitrile oxides

1,3-Dipolar cycloaddition of nitrile oxides generated in situ in the presence of variously substituted N-arylmaleimides and N-benzylmaleimide provides new pyrrolo3,4-d]izoxazoline-4,6-diones in good yields. The whole procedure could be performed in a practical and efficient one-pot operation. All the cycloadducts were isolated in excellent yields and identified by spectral studies. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 444–448, March, 2009.