Beyond blood sugar: the potential of NMR-based metabonomics for type 2 human diabetes,and the horse as a possible model |
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Authors: | Michael S Hodavance Sarah L Ralston István Pelczer |
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Institution: | (1) Department of Chemistry, Princeton University, Princeton, NJ 08544, USA;(2) Department of Animal Science, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ 08981, USA |
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Abstract: | Metabonomic analysis is a powerful tool for identifying and characterizing metabolic disorders, for example type 2 diabetes
and the metabolic syndrome. Nuclear magnetic resonance (NMR) spectroscopy is an essential tool for such analysis, with special
benefits. The review assesses the current status and potential of NMR-based metabonomics of type 2 diabetes. The horse is
proposed as a possible model for studying this condition and disease. Some examples are shown of horse blood analyses by NMR. |
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Keywords: | Metabonomics Type 2 diabetes Horses Glucose tolerance Insulin resistance NMR |
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