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Manipulating DNA writhe through varying DNA sequences
Authors:Li Dawei  Yang Zhaoqi  Zhao Guanjia  Long Yi  Lv Bei  Li Cheng  Hiew Shuhui  Ng Magdeline Tao Tao  Guo Juanjuan  Tan HongKee  Zhang Hao  Li Tianhu
Institution:Division of Chemistry and Biological Chemistry, Nanyang Technological University, 21 Nanyang Link, Singapore. lida0006@e.ntu.edu.sg
Abstract:It is demonstrated that the shapes and magnitudes of DNA writhe can be precisely manipulated solely through maneuvering the nucleotide sequence of DNA and without the assistance of topoisomerases.
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