<Emphasis Type="Italic">p</Emphasis>-(Dimethylamino)benzaldehyde modification of the Hantzsch reaction: Synthesis of 3-(1H-benzimidazol-2-yl)-5,7-dimethoxyquinolines

A three component cyclocondensation of p-(dimethylamino)benzaldehyde with 3,5-dimethoxyaniline and 2-phenacyl-1H-benzimidazoles gives previously unknown 2-aryl-3-(1H-benzimidazol-2-yl)-5,7-dimethoxyquinolines. The Hanztsch type reaction occurs in refluxing acetic acid and is accompanied by aromatization of the 1,4-dihydroquinolines formed through loss of N,N-dimethylaniline. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1792–1798, December, 2007.