| 聚(N-对丙烯酰氧苯甲酰氧基)丁二酰亚胺的合成及其共聚物与血清蛋白的固定化 |
| |
| 引用本文： | 陆承勋,顾忠伟,冯新德,王重庆,李德昌.聚(N-对丙烯酰氧苯甲酰氧基)丁二酰亚胺的合成及其共聚物与血清蛋白的固定化[J].高分子学报,1980,0(4):240-246. |
| |
| 作者姓名： | 陆承勋 顾忠伟 冯新德 王重庆 李德昌 |
| |
| 作者单位： | 北京大学化学系
(陆承勋，顾忠伟，冯新德)，北京大学生物系
(王重庆)，北京大学生物系(李德昌) |
| |
| 摘 要： | 新的丙烯酸活性酯,N-(对甲基丙烯酰氧苯甲酰氧基)丁二酰亚胺(MBOSu)及N-(对丙烯酰氧苯甲酰氧基)丁二酰亚胺(ABOSu)单体分别由对甲基丙烯酰氧基苯甲酸(MBA)、对丙烯酰氧基苯甲酸(ABA)与N-羟基丁二酰亚胺(HOSu)在环已基羰二亚胺存在下经偶联反应合成。MBOSu及 ABOSu 容易进行均聚合及与MBA或ABA进行共聚合而得到相应的反应性聚合物。P(MBOSu-MBA)共聚物是一个较好的固定化蛋白质的载体。它极易与抗血清(驴抗人A·B·O混合血清)或正常人 A·B·O混合血清反应,形成一种具有较高免疫活性的固定化免疫吸附剂。
|
| 收稿时间： | 1979-09-01 |
SYNTHESIS OF N-p-ACRYLOXYBENZOYLOXY SUCCINIMIDES AND THE USE OF ITS COPOLYMER FOR IMMOBILI-ZATION OF SERUM PROTEIN |
| |
| Lu Cheng-xun,Gu Zhong-wei,Feng Xin-de,Wang Chong-qing,Li De-chang.SYNTHESIS OF N-p-ACRYLOXYBENZOYLOXY SUCCINIMIDES AND THE USE OF ITS COPOLYMER FOR IMMOBILI-ZATION OF SERUM PROTEIN[J].Acta Polymerica Sinica,1980,0(4):240-246. |
| |
| Authors: | Lu Cheng-xun Gu Zhong-wei Feng Xin-de Wang Chong-qing Li De-chang |
| |
| Institution: | Department of Chemistry; Beijing University; Department of Biology; Beijing University |
| |
| Abstract: | Two new active esters of acrylic acids monomers, N-p-acryloxybenzoyloxy succini-mide (ABOSu) and N-p-methacryloxybenzoyloxy succinimide (MBOSu) have been synthesized and polymerized.ABOSu and MBOSu were prepared by coupling of p-acryloxybenzoic acid (ABA) or p-methacryloxybenzoie acid (MBA) with N-hydroxy succinimide in the presence of dicyclohexylcarbodimide.High molecular weight poly (ABOSu) and poly (MBOSu) were obtained by radical polymerization of the corresponding monomers.The reactive poly (MBOSu-MBA) copolymer was used to immobilize the serum protion. This immobilized protein was a hopeful bioactive solid immunoadsorbent. |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《高分子学报》浏览原始摘要信息 |
| 点击此处可从《高分子学报》下载免费的PDF全文 |
