Bioassay studies of cobalt (II) complexes of modified diamine |
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Authors: | Saeed Ur-Rehman Muhammad Ikram Sadia Rehman Shah Nawaz |
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Affiliation: | 1. Institute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Pakistan
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Abstract: | Coordination compounds of modified diamine, the basic unit of which are ethylenediamine, with that of Co (II) are prepared. The modified diamines are ethylenediaceticacid (EDDA) and N,N,N,N-tetaraethylene-1,2-diamine (TEEDA). These diamines are characterized through 1H-NMR, 13C-NMR, elemental analysis and IR techniques. Cobalt (II) complexes of these two ligands were prepared and characterized by physical measurements including elemental analysis, IR, UV-Visible, magnetic susceptibilities and conductance measurements. Antibacterial activities are also carried out in order to investigate the biological activity upon complexation. They were screened against four pathogenic bacteria like Escherichia coli, Pseudomonas aeroginosa, Klesbella pneumonia and Staphylococcus aureus. The results showed significant enhancement in activities. |
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Keywords: | EDDA TEEDA cobalt complexes antibacterial studies |
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