安乃近在蒙脱土修饰电极上的电化学行为及测定

制备了蒙脱土修饰电极,并采用循环伏安法研究了安乃近在该电极上的电化学行为。结果表明,该电极过程是一受扩散控制的不可逆过程。用方波溶出伏安法优化了实验参数,测定了浓度与峰电流Ipa的线性关系,发现Ipa与安乃近浓度在2.0×10-6~8.0×10-5mol.L-1之间呈良好的线性关系,其线性回归方程为:Ipa(μA)=-0.07784-15443.54c(μmol.L-1),r=-0.9993,检出限可达1.12×10-6mol.L-1,回收率为94.0%~108.25%。该方法可用于药物中安乃近含量的测定。

Electrochemical Behavior of Dipyrone at Montmorillonite Modified Electrode and Its Determination

The electrochemical behavior of dipyrone was studied on montmorillonite modified electrode by cyclic voltammetry.The result indicated that the process was controlled by diffusion. Determination parameters were optimized and the correlation between peak current and the concentration was studied by square wave stripping voltammetry (SWSV). A good linearity between the peak current and concentration of dipyrone in the range of 2.0×10~(-6) mol·L~(-1)～6.0×10~(-5) mol·L~(-1) was found with a linear equation of I_(pa)(μA)=-0.07784-15443.54011c(μmol·L~(-1)) and a correlative coefficient of -0.9993. The detection limit was 1.12×10~(-6) mol·L~(-1). This method can be used for the determination of dipyrone in real samples.