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Stereoselective synthesis of functionalized pyrrolidines via a [3 + 2]-annulation of N-Ts-alpha-amino aldehydes and 1,3-Bis(silyl)propenes
Authors:Restorp Per  Fischer Andreas  Somfai Peter
Institution:Organic Chemistry and Inorganic Chemistry, KTH Chemical Science and Engineering, 100 44 Stockholm, Sweden.
Abstract:An efficient protocol for stereoselective synthesis of densely functionalized pyrrolidines by a 3 + 2]-annulation of N-Ts-alpha-amino aldehydes and 1,3-bis(silyl)propenes is described.
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