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Chemistry of heteroanalogs of isoflavones
Authors:Khilya  V P  Kupchevskaya  I P  Salikhova  A I  Grishko  L G  Babichev  F S  Kirillova  L G
Institution:(1) T. G. Shevchenko Kiev State University, 252017 Kiev
Abstract:Condensation of 2-pyridylacetonitrile with polyphenols gave the corresponding agr-(2-pyridyl)-acetophenones, which were converted to the pyridine analogs of natural isoflavones and to 3-pyridylchromones with methyl, trifluoromethyl, and ethoxycarbonyl groups in the 2 position. The antimicrobial activity of 3-pyridylchromones and their reaction with alkylating and acylating agents and phosphorus pentasulfide were investigated.See 1] for communication V.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1180–1185, September, 1977.
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