A novel quinoline alkaloid possessing a 7-benzyl group from the centipede, Scolopendra subspinipes. |
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| Authors: | N Noda Y Yashiki T Nakatani K Miyahara X M Du |
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| Affiliation: | Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan. noda@pharm.setsunan.ac.jp |
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| Abstract: | The novel quinoline alkaloid scolopendrine was isolated from the centipede, Scolopendra subspinipes mutilans L. Koch. The structure was determined to be 2-hydroxy-7-[(4-hydroxy-3-methoxyphenyl)methyl]-3-methoxy-8-quinolyl sulfate on the basis of high-resolution electron-spray ionization mass spectroscopy and two-dimensional NMR spectral data. Unlike quinoline alkaloids so far reported, scolopendrine is unique in having a 7-benzyl moiety in the quinoline ring. |
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