| Synthesis, Crystal structure and Antioxidant of 3,5-Dihydroxy-N＇-（5-bro-2-hydroxybenzylidene） benzohydrazide Hydrate |
| |
| 作者姓名： | SUN Zhen-Gao LIAN Fang ZHANG Jian-Wei SUN Jin-Long GUO Ying ZHANG Ning DIAO Yun-Peng |
| |
| 作者单位： | [1]Affiliated Hospital of Shandong University of Traditional Chinese Medicine ＆ Pharmaceuticals, Jinan 250011, China [2]Shandong University of Traditional Chinese Medicine ＆ Pharmaceuticals, Jinan 250014, China [3]College of Pharmacy, Dalian Medical University, Dalian, Liaoning 116044, China |
| |
| 基金项目： | This study was supported by the National Natural Science Foundation of China，Shandong province natural funded Projects，Shandong province traditional Chinese medical science and technology development programs |
| |
| 摘 要： | A new compound, 3,5-dihydroxy-N′-(5-bro-2-hydroxybenzylidene)benzohydrazide hydrate, has been synthesized and characterized by single-crystal X-ray diffraction. The title compound crystallizes in a monoclinic system, space group P21/c with a = 14.267(6), b = 8.079(4), c = 13.157(6) , β = 108.114(4), Z = 4, V = 1441.4(11) 3, Dc = 1.701 g/cm3, F(000) = 744.0, μ = 2.878 and S = 1.021. The final R = 0.0457 and wR = 0.1149 for 3500 observed reflections with I > 2 (I). The ability with which the compound scavenges free radicals of ABTS and DPPH, IC50, is 34.13 and 101.6 μM, respectively.
|
| 关 键 词： | Schiff base compound crystal structure antioxidant activity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
