Aminoacyl derivatives of nucleosides,nucleotides, and polynucleotides |
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Authors: | P P Purygin A A Kraevskii B P Gottikh |
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Institution: | (1) Institute of Molecular Biology, Academy of Sciences of the USSR, USSR |
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Abstract: | Conclusions A method for the synthesis of 3 (2 )-O-aminoacylnucleoside 5 -di- and triphosphates has been developed which is based on the condensation of the imidazolides of N-tert-butoxycarbonylamino acids with nucleoside di-and triphosphates and subsequent removal of the tert-butoxycarbonyl protection by treatment with hydrogen chloride in absolute ether.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1084–1087, May, 1968. |
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