School of Pharmaceutical Sciences, Central South University, Changsha 410013, China ; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 51006, China
Abstract:
One-pot synthesis of substituted pyrano- and furano3,2-c]quinoline derivatives from appropriately substituted anilines, substituted benzaldehydes and dienophiles via Povarov reaction catalyzed by HCl-ethanol were reported.Good to excellent yields with high diastereoselectivity were obtained in all entries tested.