Intramolecular direct arylation in an A,C-functionalized calix[4]arene |
| |
Authors: | Barton Olaf G Neumann B Stammler H-G Mattay Jochen |
| |
Institution: | Organische Chemie I, Universit?t Bielefeld, Universit?tsstr. 25, 33501 Bielefeld, Germany. oc1jm@uni-bielefeld.de |
| |
Abstract: | A recently developed efficient method for intramolecular direct arylation is employed on a doubly functionalized calix4]arene fixed in the cone conformation. The reaction takes place in high yield leading to meta substituted calix4]arenes. The functionalities are located at two opposite aromatic rings and the two possible diastereomers are obtained in a 1:1 ratio. Full sets of data including crystal structures for both isomers are presented. The NMR data reveal that even at temperatures up to 120 degrees C both isomers are fixed in a flattened cone conformation with the substituted aromatic units pointing outwards. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|