毛冬青皂苷甲的18,19-脱水皂苷元二甲酯的红外光谱分子内氢键效应的研究

有机化合物稀溶液的红外光谱用来研究分子内氢键是否存在,存在的形式等,以确定分子的构型和构象。毛冬青皂甙甲 IlexsaponinA 是从民间治疗冠心病有效药物毛冬青Ilex

Infrared Spectroscopic Determination of the Intramolecular Hydrogen Bonding of 18,19-Anhydro Sapogenin Dimethyl Ester of Ilexsaponin A

The intramolecular hydrogen bonding of 18,19-anhydro-sapogenindimethyl ester of Ilexsaponin A,the hydrolysis product of a new triterpenoid saponin isolated from Ilex pubescens Hook et Am,was studied by infrared spectroscopic tech-nique,and an assignment was made of its stereochemical configurations on the basisof comparison the effect of concetrations and the peak shift before and after deuterra-tion.Included in this paper is a detailed discussion on the optimum experimental con-ditions,such as sample concentrations,thickness of sample cells and so on,necessaryfor carrying out the determination.