甾体席夫碱荧光探针的微波合成及其对金属离子的识别

采用石胆酸与2-羟基-1-萘甲醛为原料,合成了一种新型甾体席夫碱结构荧光探针(L),其结构经NMR,IR,ESI-MS和元素分析表征。在pH 7.0缓冲溶液溶液中,探针L可以高选择性荧光识别Al^3+,检测限为8.0 nmol/L,适用范围为pH 6~10。当Al^3+与探针L配位时,生成1:1型配合物(L-Al^3+),在365 nm紫外灯照射下,由无色变成亮蓝色强荧光。

Microwave synthesis of steroids Schiff base fluorescent probe and its recognition of metal ions

The titled compound probe(L)was synthesized by using lithochiolic acidand 2-hydroxy-1-naphthaldehyde as starting materials,and its structure was characterized by NMR,IR,ESI-MS and elemental analysis.In ethanol/Tris(pH 7.0)solution,the probe L can high-selectively recognize Al3+with fluorescence response,the experimental results demonstrated that the detection limit was 8.0 nmol/L,with appropriate p H range of 6-10.When Al3+was coordinated with probe L,1:1(V/V)type complex(L-Al^3+)formed and the system exhibited strong bright-blue fluorescence under 365 nm UV lamp irradiation.