Urinary steroids in premenopausal women with breast cancer at the time of surgery |
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| Authors: | V Poór S Juricskay I Szabó K Kett |
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| Institution: | (1) Central Research Laboratory, Faculty of Medicine, University of Pécs, 12 Szigeti u, 7643 Pécs, Hungary;(2) Department of Orthopaedia, Faculty of Medicine, University of Pécs, 13 lfjuság u, 7624 Pécs, Hungary;(3) Department of Surgery, County Hospital, Faculty of Medicine, University of Pécs, 2 Garai u, 7624 Pécs, Hungary |
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| Abstract: | Summary Urinary steroid metabolites were measured by capillary gas chromatogaphy in 10 premenopausal women with operable breast cancer
and 16 control women a day before operation. There were significant decreases in the levels of androsterone (A), main cortisol
(F) metabolites/tetrahydrocortisone (THE), tetrahydrocortisol (THF), allo-tetrahydrocortisol (aTHF)/and β-cortolone (βCL).
The lower adrenal function accompanies breast cancer in premenopausal women. As the number of patients included in the study
is small our conclusions must be considered as preliminary.
Presented at Balaton Symposium '01 on High-Performance Separation Methods, Siófok, Hungary, September 2–4, 2001 |
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| Keywords: | Gas chromatography Solid phase extraction Methoxime-silyl derivate Urinary steroids Breast cancer |
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