Lipoxygenase inhibiting constituents from Indigofera hetrantha |
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Authors: | Aziz-Ur-Rehman Malik Abdul Riaz Naheed Ahmad Habib Nawaz Sarfraz Ahmad Choudhary Muhammad Iqbal |
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Affiliation: | International Centre for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Pakistan. |
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Abstract: | A lignan and two acylphloroglucinols have been isolated from the ethyl acetate soluble fraction of the whole plant of Indigofera hetrantha. Their structures have been assigned on the basis of spectral analysis including 1D and 2D NMR techniques. Compounds 1-3 displayed promising inhibitory potential against enzyme lipoxygenase in concentration-dependent manner. |
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