Synthesis of the penta-oxazole core of telomestatin in a convergent approach to poly-oxazole macrocycles |
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| Authors: | Marson Charles M Saadi Mona |
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| Affiliation: | Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London, WC1H 0AJ, UK. c.m.marson@ucl.ac.uk |
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| Abstract: | A protocol for the construction of poly-oxazoles with consecutive 2,4'-linkages is described, and has afforded an efficient route to a penta-oxazole which demarcates a route to telomestatin and related macrocyclic poly-oxazole systems. |
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