A novel water-soluble Hantzsch 1,4-dihydropyridine compound that functions in biological processes through NADH regeneration |
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| Authors: | Sambongi Yoshihiro Nitta Hajime Ichihashi Kayoko Futai Masamitsu Ueda Ikuo |
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| Affiliation: | Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan. ueda@sanken.osaka-u.ac.jp |
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| Abstract: | A novel Hantzsch 1,4-dihydropyridine derivative could function in an organic solvent-free solution, and thus it could function in biological systems. These functions can be accomplished through regeneration of the reduced form of nicotinamine adenine dinucleotide (NADH), an essential compound for living organisms. The results obtained here demonstrate the usefulness of a water-soluble Hantzsch 1,4-dihydropyridine derivative and its wide applicability as a chemical energy source, which drives various biological processes efficiently. |
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