Formation of LacNAc mimetics employing novel donor substrates for enzymatic beta 1-->4 galactosylation |
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Authors: | Weingarten Saskia Thiem Joachim |
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Affiliation: | Institute of Organic Chemistry, Hamburg University, Martin-Luther-King-Platz 6, D-20146, Hamburg, Germany. |
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Abstract: | In examining C-6 modified 4-nitrophenyl beta-D-galactopyranosides as donor structures the beta-galactosidase (Bacillus circulans) revealed an unexpectedly broad substrate specificity which allowed successful syntheses of various disaccharide components. |
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