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A facile synthesis of functionally complex isoxazole derivatives |
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| Authors: | NR Natale Chorng-Shyr Niou |
| Institution: | Department of Chemistry, University of Idaho, Moscow, ID 83843 U.S.S.R. |
| Abstract: | Metalation of 2(4′-Isoxazolyl)-Δ2-oxazolines takes place initially and selectively on the C-5′-alkyl group. Subsequent metalation also proceeds at this position. Selective deprotection of the oxazoline was accomplished without disturbing the isoxazole ring. |
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