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Enhancing cell recognition by scrutinizing cell surfaces with a nanoparticle array
Authors:Zhou Hongyu  Jiao Peifu  Yang Lei  Li Xi  Yan Bing
Affiliation:Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Abstract:We report a dual-ligand nanoparticle array approach for discerning cells that have different surface receptor profiles surrounding a common primary receptor expressed at high or low levels. The achieved differentiation provides nanoparticles the ability for potential applications in treatment of patients at a personalized medicine level for drug delivery and radiation therapy with a much better safety profile.
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