Enhancing cell recognition by scrutinizing cell surfaces with a nanoparticle array |
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Authors: | Zhou Hongyu Jiao Peifu Yang Lei Li Xi Yan Bing |
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Affiliation: | Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States. |
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Abstract: | We report a dual-ligand nanoparticle array approach for discerning cells that have different surface receptor profiles surrounding a common primary receptor expressed at high or low levels. The achieved differentiation provides nanoparticles the ability for potential applications in treatment of patients at a personalized medicine level for drug delivery and radiation therapy with a much better safety profile. |
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