Non-metathesis reactions of ruthenium carbene catalysts and their application to the synthesis of nitrogen-containing heterocycles |
| |
Authors: | Arisawa Mitsuhiro Terada Yukiyoshi Takahashi Kazuyuki Nakagawa Masako Nishida Atsushi |
| |
Institution: | Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. arisawa@pharm.hokudai.ac.jp |
| |
Abstract: | Non-metathesis reactions of ruthenium carbene catalysts, such as olefin isomerization, hydrogenation, radical reaction, activation of silane, cyclopropanation, epimerization cocyclopropane, 3 + 2] cycloaddition, and cycloisomerization, are summarized. The utility of these reactions was demonstrated by the synthesis of indole using olefin isomerization and subsequent ring-closing metathesis, the synthesis of indoline using cycloisomerization, and the synthesis of the putative structure of fistulosin using cycloisomerization as a key step. |
| |
Keywords: | ruthenium isomerization cycloisomerization heterocycles indole |
本文献已被 PubMed 等数据库收录! |
|