| 过饱和度、反应物化学计量比及离子强度对草酸钙晶体生长的影响 |
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| 引用本文： | 郑辉,李祥平,欧阳健明. 过饱和度、反应物化学计量比及离子强度对草酸钙晶体生长的影响[J]. 无机化学学报, 2005, 21(9): 1375-1378 |
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| 作者姓名： | 郑辉 李祥平 欧阳健明 |
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| 作者单位： | 暨南大学生物矿化与结石病防治研究所,化学系,广州,510632 |
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| 基金项目： | 国家自然科学基金(No.20471024)，国家自然科学基金重点项目(No.20031010)，广东省“千百十工程”优秀人才培养基金(No.Q02060) |
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| 摘 要： | 肾结石是一种普遍的疾病,全球的发病率约为10%,且其复发率高。2003年欧洲的一项统计表明,尿石患者第一次复发率为40%[1]。草酸钙(CaOxa)是肾结石的主要成分,其体外模拟引起了人们广泛的关注[2,3]。然而,普通溶液体系的模拟环境不能充分反映尿石的形成环境,用类似细胞膜的有序分
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| 关 键 词： | 草酸钙； 过饱和度； 离子强度； 化学计量比； 凝胶； 尿结石 |
| 文章编号： | 1001-4861(2005)09-1375-04 |
| 收稿时间： | 2005-02-22 |
| 修稿时间： | 2005-05-09 |
Effect of Supersaturation, Stoichiometrical Ratio and Ionic Strength on Crystallization of Calcium Oxalate |
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| ZHENG Hui,LI Xiang-Ping and OUYANG Jian-Ming. Effect of Supersaturation, Stoichiometrical Ratio and Ionic Strength on Crystallization of Calcium Oxalate[J]. Chinese Journal of Inorganic Chemistry, 2005, 21(9): 1375-1378 |
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| Authors: | ZHENG Hui LI Xiang-Ping OUYANG Jian-Ming |
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| Affiliation: | Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou 510632,Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou 510632 and Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou 510632 |
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| Abstract: | The effect of supersaturation, oxalate/calcium stoichiometrical ratio (Oxa2-/Ca2+) and ionic strength on the crystallization of calcium oxalate (CaOxa) was investigated in gel systems by a double diffusion technique. The supersaturation affects the morphology, phase composition, and aggregation of CaOxa crystals. To a certain concentration, the effect of Oxa2- ions on the aggregation of calcium oxalate monohydrate (COM) was much stronger than that of Ca2+ ions. It indicated that the increase of the concentration of Oxa2- ions can more efficiently promote the formation of CaOxa stones. The increase of ionic strength and the molar ratio of Ca2+/ Oxa2- also promotes the aggregation of COM crystals. |
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| Keywords: | calcium oxalate supersaturation ionic strength stoichiometrical ratio gel urinary stone |
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