Heteropoly acid supported on activated natural clay-catalyzed synthesis of 3,4-dihydropyrimidinones/thiones through Biginelli reaction under solvent-free conditions |
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| Authors: | Karuppaiah Selvakumar Thangamariyappan Shanmugaprabha Murugan Kumaresan |
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| Affiliation: | Department of Chemistry, V.H.N. Senthikumara Nadar College (Autonomous), Virudhunagar, India |
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| Abstract: | Dihydropyrimidinones/thiones (DHPM’s) have been prepared by one-pot condensation of methyl acetoacetate, aldehydes, urea/thiourea in the presence of heteropoly-11-tungsto-1-vanadophosphoric acid, H4[PVW11O40]?·?32H2O, (HPV) supported on activated natural clay (HPVAC) under solvent-free reaction condition have been proposed. The DHPM derivatives were identified through elemental analysis and melting point measurements and characterized by FT-IR, 1H-NMR, 13C-NMR spectroscopic methods. |
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| Keywords: | 3,4-Dihydropyrimidinones/thiones heteropoly acid multi-component synthesis natural clay |
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