Humic-based bionanocomposites containing stable paramagnetic gold nanoparticles for prospective use in pharmaceuticals |
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Authors: | Spartak S Khutsishvili Marina V Lesnichaya Tamara I Vakul’skaya Gania Dolmaa Galina P Aleksandrova Aleksandr L Rakevich |
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Institution: | 1. A.E. Favorsky Irkutsk Institute of Chemistry of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, Russia;2. Chemistry and Chemical Technology Institute of the Mongolian Academy of Sciences, Ulaanbaatar, Mongolia;3. Irkutsk Branch of the Institute of Laser Physics of the Siberian Branch of the Russian Academy of Sciences, Irkutsk, Russia |
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Abstract: | Structural peculiarities and supramolecular organization of medicinally promising nanocomposites, synthesized from humic substances, which essentially differ depending on decomposition degree, have been studied using electron spin resonance, transmission electron, and confocal laser scanning microscopy techniques and some other modern physical–chemical methods. It is shown that stable zero-valent gold nanoparticle of about 10–17?nm in size are formed in a natural macromolecular matrix. The nanocomposites obtained turn out to be stable in aggregative state for a long time and preserve their properties that are extremely important for prospective medicinal substances. |
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Keywords: | ESR gold humic substance nanocomposite nanoparticles |
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