Sometimes intermediates. Do the job! |
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| Authors: | Hilgenfeld Rolf Pumpor Ksenia |
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| Affiliation: | Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany. |
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| Abstract: | The SARS coronavirus main proteinase is a prime target for antiviral therapy. In this issue of Chemistry & Biology, Wu et al. describe potent inhibition of the enzyme by benzotriazole esters, which were originally obtained as intermediates in the synthesis of lopinavir derivatives . |
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