| 新的19-降海绵烷二萜的分离及结构确定 |
| |
| 引用本文： | 苏镜娱,林翠梧,曾陇梅,闫素君,冯小龙,蔡继文.新的19-降海绵烷二萜的分离及结构确定[J].高等学校化学学报,2003,24(5):817-819. |
| |
| 作者姓名： | 苏镜娱 林翠梧 曾陇梅 闫素君 冯小龙 蔡继文 |
| |
| 作者单位： | 1. 中山大学化学与化工学院;
2. 中山大学化学与化工学院分析测试中心, 广州 51027;
3. 广西大学化学系, 南宁 530004 |
| |
| 基金项目： | 国家自然科学基金(批准号:29932030)，国家高科技研发计划(海洋863)(批准号:2001AA620403)资助 |
| |
| 摘 要： | 从海洋海绵Spongiazimoccaaubspeclesirregularia中分离到一种新的19-降海绵烷二萜(ZimoclactoneA,1)和胆甾-5,7-二烯-3β-醇,化合物1的化学结构和立体化学通过波谱方法和X射线单晶衍射分析确定,化合物1对P388肿瘤细胞具有中等程度的细胞毒活性.
|
| 关 键 词： | 海绵 19-降海绵烷二萜 Spongia zimocca X射线单晶衍射分析 |
| 文章编号： | 0251-0790(2003)05-0817-03 |
| 收稿时间： | 2002-04-12 |
Separation and Structure Determination of a New 19-nor-Spongian Diterpenoid |
| |
| SU Jing-Yu,LIN Cui-Wu,ZENG Long-Mei,YAN Su-Jun,FENG Xiao-Long,CAI Ji-Wen.Separation and Structure Determination of a New 19-nor-Spongian Diterpenoid[J].Chemical Research In Chinese Universities,2003,24(5):817-819. |
| |
| Authors: | SU Jing-Yu LIN Cui-Wu ZENG Long-Mei YAN Su-Jun FENG Xiao-Long CAI Ji-Wen |
| |
| Institution: | 1. School of Chemistry and Chemical Engineering;
2. Instrumentation Analysis and Research Center, Zhongshan University, Guangzhou 510275;
3. Department of Chemistry, Guangxi University, Nanning 530004, China |
| |
| Abstract: | A new 19-nor-spongian diterpene, zimoclactone A(1) together with a known compound, cholest-5,7-dien-3β-ol(2) were isolated from the Spongia zimocca aubspecles irregularia of marine sponge. The structure of compound 1 was determined by spectroscopic methods as well as X-ray diffraction analysis. Compound 1 showed a moderate cytotoxic activity against P388 cell lines. |
| |
| Keywords: | Marine sponge 19-nor-Spongian diterpenoid Spongia zimocca X-ray single crystal diffrac- tion analysis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《高等学校化学学报》浏览原始摘要信息 |
| 点击此处可从《高等学校化学学报》下载免费的PDF全文 |
